Fundus photography involves photographing the rear of an eye; also known as the fundus. Specialized fundus cameras consisting of an intricate microscope attached to a flash enabled camera are used in fundus photography. The main structures that can be visualized on a fundus photo are the central and peripheral retina, optic disc and macula. Fundus photography can be performed with colored filters, or with specialized dyes including fluorescein and indocyanine green. Fundus photography is used to document clinical signs and to help monitor progression reliably.Fundus photography is a valuable clinical tool for evaluating progression of retinopathy in individual patients and in participants in clinical trials. Photography is used in clinical practice to document the status of retinopathy and effects of treatment.The models and technology of fundus photography has advanced and evolved rapidly over the last century. Fundus photographs are also used to document abnormalities of disease process affecting the eye, and/or to follow up on the progress of the eye condition/disease such as diabetes, age-macular degeneration(AMD), glaucoma, Neoplasm of the choroid, cranial nerves, retinal or eyeball, etc.In patients with diabetes mellitus, regular fundus screening examinations (once every 6 months to 1 year) are important to screen for diabetic retinopathy as visual loss due to diabetes can be prevented by retinal laser treatment if retinopathy is spotted early.